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Looking for the height genes
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In the largest Genome-Wide Association Study so far with ~5.4 mn people, researchers across the world came together to form the GIANT Consortium. GR Chandak from CCMB was a part of this. They found more than 12,000 genetic variants associated with human height. Across the genome, these variants are more likely to be clustered close to genes already known to be associated with growth disorders.
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Who are the Nepalis, genetically speaking?
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The Himalayan Mountain range of Nepal has served as a geographical barrier to migration, while at the same time its valleys have served as continuous trade and exchange. So, it is intriguing to know more about the ancestry of Nepali population. A recent study led by Thangaraj on different ethnic groups of Nepal show that population from Kathmandu and Eastern Nepal have derived their maternal
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ancestry from the lowland population rather than the highlanders.
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Antidote against SARS-CoV-2 - one step closer to the market
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The antidote against SARS-CoV-2 (an F(ab’)2 antibody fragment) co-developed by scientists at CCMB led by H Krishnan, University of Hyderabad and VINS Bioproducts Pvt Ltd has successfully completed its phase 2 trials.
Krishnan's lab characterized the virus and optimized methods to generate inactivated viral antigens that could be used for immunization in equines. Virus grown in large-scale cultures in CCMB were inactivated and it was injected into equines to generate antibodies.
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Avni Blotra for securing the Royal Society for Tropical Medicine and Hygiene Early Career Grants Award 2022. She works with Karthikeyan Vasudevan and will look into toxicity of venom components that stay after partial neutralisation by the Indian polyvalent antivenom against snakebites.
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EMBO Lecture Series starts in CCMB
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With advances in stem cell technologies it's time to think miniature lab-grown organs, the microphysiological systems, for biological studies and testing. They offer alternates to testing in animals when we actually are seeking the effects on human cells and systems. The Centre for Predictive Human Model Systems at Atal Incubation Centre-CCMB and CCMB have organized a 5-day EMBO lecture course on microphysiological systems. Several renowned researchers from across the globe conducted the course for 100 participants.
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CCMB's Guest Lecture Series
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CCMB has started a guest lecture series. Each month, an eminent scientist will be invited for a talk followed by an interactive session with our students.
We kickstarted with Prof BJ Rao, Vice-Chancellor, University of Hyderabad. As an accomplished biochemist, he spoke of how biology might seem counter-intuitive a lot of times but is very robust for specific contexts.
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CCMB's startup incubator, Atal Incubation Centre - CCMB celebrated its five successful years. In these five years, they have incubated 80 biotech startups with cutting-edge facilities, technical and intellectual expertise. During the event, they announced their focus on reaching out to the tier-2 cities in the coming months.
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Connecting the Nobel Prize 2022 winning work with work at CCMB
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The first ancient DNA lab in India started at CCMB, and Thangaraj has been a part of its development since the very beginning. Hear him speak of ancient DNA research - that won the Nobel Prize for Physiology/Med recently as well as work from India.
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We celebrated Wildlife Week with about 100 young people of Hyderabad today. We heard their ideas on keystone species, livelihoods and wildlife around them through their art and presentations. Reminder for us to partner with the young closely.
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Plants move from one place to another, and their surroundings help them do that. Check out our latest zine based on Meghna Krishnadas' research. It tells us how plant lives are intertwined with human activities.
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What do plant seeds contain?
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Plant seeds contain plant embryos. Take a look at how they are protected inside seeds, and their development over time.
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How do squirrels manage to store seeds?
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Follow squirrels in their ways of learning of how to find and store their nuts. Karthikeyan Vasudevan helps us understand how these might be different in animals growing up in wild and in labs.
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Please send us your feedback at socialmedia[at]csirccmb[dot]org. Looking forward to them.
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