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10,000 Genome Project is completed!
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The 10,000 Genome Project led by CCMB, IGIB, NIBMG and CBR at IISc with 16 other institutes is now completed! And this has been a key milestone towards finding Indian population specific genetic variants and working towards more effective healthcare.
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Did you think insects are all the same?
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Do flying insects share the same body-formation timelines? The environment in which they have survived over millions of years probably decides that. For example, in this study, Khushboo, Sunil, Baskar with Dhananjay Chaturvedi looked at Anopheles stephensi mosquito development in great detail through micro-CT scanning. There are apparent similarities with the fruit fly, a darling of many biologists. But most importantly, critical differences make us think about how our understanding of general insect formation should change. Findings in this study underline the need for a better understanding of individual pest or disease-vector development, with hopes of controlling them.
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What will improve cancer diagnostics?
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Cancer diagnosis remains a painful and expensive process that many women refrain from using. Here is a list of potential microRNA biomarkers that Lekha Dinesh Kumar's work has highlighted for detecting invasive ductal carcinoma in breast cancer.
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How do plants overcome stress?
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When plant cells undergo stress such as high salinity or drought, they produce different kinds of aldehydes. These help in overcoming the stress by altering the chemical reactions in the cells. However, these aldehydes can also interfere with the protein translation machinery in the cells, and causes toxicity. Sankaranarayanan’s lab have shown that DTD2 in plant cells protect their protein translation machinery from the toxic effects of aldehydes.
In this study, they find in excess of DTD2, plants show an extensive root growth, grow better and are able to tolerate multiple kinds of aldehydes in large quantities. Using this understanding, they raise the possibility of developing crops with high DTD2 that can withstand stress more effectively.
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Outliers open up new fields of studies
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Pradeep Kumar and Rajan Sankaranarayanan write on how Paul Berg and Donald Crother's findings that were against the understanding of those times led their work to unexpected turns of unraveling evolution of different life forms.
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An ode to the CCMB Founder
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CCMB celebrated the birth anniversary of PM Bhargava as its Founder's Day on 22 Feb. It was a day for the present students to connect with alumni, and CCMB to remember the place of art and science that it is!
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The tale of toxic Arthropods
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If you are one of those who creep out at the many-legged crawlies, this one's for you. In this article, Aditi will take you into their worlds, tell you about the toxins they carry, and how these toxins are helping us as well!
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Tackling aquatic invasions systematically
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While lantana plants feature commonly in the discussions on invasive species, those on the changes in the aquatic ecosystems are rather primitive. In this article, Gopi Krishnan and Somdatta Karak write about collecting better data on the effects of invasive fishes on ecosystems to identifying the priority species to developing ways of monitoring and managing them - India needs to step up on all these fronts. This was inspired from a consultative meeting with aquatic ecosystem experts at LaCONES-CCMB in Aug 2023.
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Phenome India - Creating a database of health indicators
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Across CCMB, IICT, NGRI and IGIB, CSIR is leading the Phenome India project. The project collects blood samples to build an Indian database of health parameters and develop personalized risk scores for Indian populations.
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Many congratulations to Santosh Chauhan for the Sun Pharma Research Fellowship - 2023
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Science is going to unusual spaces
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CCMB participated in the Science Day celebrations at Rashtrapati Nilayam from 26-28 Feb. This was our place to interact with young people on genes and genetic diseases.
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Training for lab leaders to become better managers
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